Meaning of amitriptyline in English:


Pronunciation /ˌamɪˈtrɪptɪliːn/


mass nounMedicine
  • An antidepressant drug of the tricyclic group, with a mild tranquillizing action.

    ‘Tricyclic antidepressants, including amitriptyline, can cause weight gain, drowsiness, and anticholinergic symptoms.’
    • ‘The most useful drugs are anticonvulsants, especially gabapentin and carbamazepine, and tricyclic antidepressants, especially amitriptyline.’
    • ‘Of the tricyclic antidepressants, amitriptyline appears to be the most efficacious in the treatment of diabetic neuropathy when compared to placebo.’
    • ‘For example, the anti-depressant drug amitriptyline has been shown to help prevent some chronic headaches when taken in small doses (lower than that used to treat depression) before going to bed every night.’
    • ‘Tricyclic antidepressants, such as amitriptyline and desipramine, have shown excellent pain control.’


1960s from ami(ne) + tri- + (he)ptyl+ -ine.