noun
mass nounMedicineA cytotoxic drug used in the treatment of cancer.
‘Prednisone, methotrexate, and cyclophosphamide or chlorambucil are drugs which can be used to help stop the scar formation in the lungs.’- ‘This review focuses on the most commonly used and accepted chemotherapy agents in the treatment of these diseases: cyclophosphamide, chlorambucil, and methotrexate.’
- ‘Combinations of chlorambucil, Prednisone or cyclophosphamide and a new drug Fludarabine are used in treatment.’
- ‘The patient's treatment included chlorambucil and radiolabeled rituximab.’
- ‘Methotrexate and chlorambucil have been used as steroid-sparing agents, but have toxicities of their own.’
Origin
1950s from chlor(oethyl)am(inophenyl)bu(tyric acid), the systematic name, + -cil.
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