Meaning of chlorambucil in English:


Pronunciation /klɔːˈrambjʊsɪl/


mass nounMedicine
  • A cytotoxic drug used in the treatment of cancer.

    ‘Prednisone, methotrexate, and cyclophosphamide or chlorambucil are drugs which can be used to help stop the scar formation in the lungs.’
    • ‘This review focuses on the most commonly used and accepted chemotherapy agents in the treatment of these diseases: cyclophosphamide, chlorambucil, and methotrexate.’
    • ‘Combinations of chlorambucil, Prednisone or cyclophosphamide and a new drug Fludarabine are used in treatment.’
    • ‘The patient's treatment included chlorambucil and radiolabeled rituximab.’
    • ‘Methotrexate and chlorambucil have been used as steroid-sparing agents, but have toxicities of their own.’


1950s from chlor(oethyl)am(inophenyl)bu(tyric acid), the systematic name, + -cil.