Meaning of cyclophosphamide in English:



mass nounMedicine
  • A synthetic cytotoxic drug used in treating leukaemia and lymphoma and as an immunosuppressive agent.

    • ‘A combination of two immunosuppressive drugs, cyclophosphamide and fludarabine, was given with the intent to knock out the patient's immune system to allow the foreign donor immune cells to take hold.’
    • ‘The patient was treated with cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy starting in August 1998.’
    • ‘Adjuvant therapy, multidrug chemotherapy was carried out with methotrexate, cyclophosphamide, doxorubicin, vincristine, and prednisone.’
    • ‘The benefit of cytotoxic agents such as cyclophosphamide has not yet been established.’
    • ‘Most patients in the Danish study were treated with cyclophosphamide, methotrexate, and fluorouracil chemotherapy, the dose and schedule of which have been criticised.’
    • ‘For severe ocular involvement, patients are treated with systemic steroids, along with cyclophosphamide or azathioprine.’
    • ‘Before a transplant takes place, the patient's abnormal bone marrow is destroyed through total body radiation, in combination with the drug cyclophosphamide.’
    • ‘The patient was treated with adjuvant chemotherapy consisting of doxorubicin and cyclophosphamide for 4 cycles; she handled the treatment well.’
    • ‘The patient did well postoperatively, and chemotherapy consisting of cyclophosphamide, vincristine, adriamycin, and prednisone was initiated.’
    • ‘Anticancer agents such as cisplatin, cyclophosphamide, and methotrexate slow gastric emptying.’