Meaning of cyclophosphamide in English:


Pronunciation /ˌsʌɪklə(ʊ)ˈfɒsfəmʌɪd/


mass nounMedicine
  • A synthetic cytotoxic drug used in treating leukaemia and lymphoma and as an immunosuppressive agent.

    ‘A combination of two immunosuppressive drugs, cyclophosphamide and fludarabine, was given with the intent to knock out the patient's immune system to allow the foreign donor immune cells to take hold.’
    • ‘The patient was treated with cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy starting in August 1998.’
    • ‘Adjuvant therapy, multidrug chemotherapy was carried out with methotrexate, cyclophosphamide, doxorubicin, vincristine, and prednisone.’
    • ‘The benefit of cytotoxic agents such as cyclophosphamide has not yet been established.’
    • ‘Most patients in the Danish study were treated with cyclophosphamide, methotrexate, and fluorouracil chemotherapy, the dose and schedule of which have been criticised.’
    • ‘For severe ocular involvement, patients are treated with systemic steroids, along with cyclophosphamide or azathioprine.’
    • ‘Before a transplant takes place, the patient's abnormal bone marrow is destroyed through total body radiation, in combination with the drug cyclophosphamide.’
    • ‘The patient was treated with adjuvant chemotherapy consisting of doxorubicin and cyclophosphamide for 4 cycles; she handled the treatment well.’
    • ‘The patient did well postoperatively, and chemotherapy consisting of cyclophosphamide, vincristine, adriamycin, and prednisone was initiated.’
    • ‘Anticancer agents such as cisplatin, cyclophosphamide, and methotrexate slow gastric emptying.’