Meaning of de novo in English:

de novo

Pronunciation /deɪ ˈnəʊvəʊ/ /diː ˈnəʊvəʊ/


  • From the beginning; anew.

    ‘in a pure meritocracy, everyone must begin de novo’
    • ‘Both the Federal Reserve and the Office of the Comptroller of the Currency recommend that Congress remove outdated barriers to de novo interstate branching.’


  • Starting from the beginning.

    • ‘a general strategy for de novo protein design’


Latin, literally ‘from new’.