Meaning of DNase in English:


Pronunciation /ˌdiːɛnˈeɪz/


mass nounBiochemistry
  • An enzyme which catalyses the hydrolysis of DNA into oligonucleotides and smaller molecules.

    Also called deoxyribonuclease

    ‘We believe that it is because of specific digestion of the NA molecules by DNase and RNase.’
    • ‘The combination of streptokinase and streptococcal DNase produces marked reductions in viscosity, and these can only be attributed to the presence of the streptodornase.’
    • ‘Both unswollen and swollen nuclei could be further enlarged with the addition of DNase and RNase.’
    • ‘The RNA was treated with DNase to remove residual DNA and then it was reverse transcribed also as previously described.’
    • ‘Cells were broken either by a French cell press or lysozyme with a small amount of DNase 1.’


1940s from DNA+ -ase.