Meaning of extrapyramidal in English:


Pronunciation /ˌɛkstrəpɪˈramɪd(ə)l/


Anatomy Medicine
  • Relating to or denoting motor nerves that descend from the cortex to the spine but are not part of the pyramidal system.

    ‘extrapyramidal symptoms’
    • ‘Common side effects of antipsychotics include sedation, anticholinergic effects, orthostatic hypotension, extrapyramidal symptoms and tardive dyskinesia.’
    • ‘In the elderly, antipsychotic medications can cause serious side effects, such as extrapyramidal symptoms and tardive dyskinesia.’
    • ‘These agents also have safety issues, particularly those of acute extrapyramidal symptoms, tardive dyskinesia, and neuroleptic malignant syndrome.’
    • ‘Most of these drugs are designed to control negative symptoms and produce fewer extrapyramidal side effects than conventional medications.’
    • ‘New antipsychotic medications such as olanzapine and risperidone often can effectively control schizophrenic symptoms without the extrapyramidal side effects of traditional agents.’