1US Of work, a workplace, etc.: organized according to the specialized function of individual workers or departments; relating to or characterized by such a system of organization.
Of a molecule, or one of its bonds or atoms: that has had a functional group introduced in order to modify the chemical behaviour of the molecule.
Of a material: that has had molecules or nanoparticles attached to its surface in order to modify its physical or chemical properties; (of a surface) modified in this way.
Mid 19th century (in an earlier sense). From functionalize + -ed.