noun

• A congenital condition in which the rectum and part of the colon fail to develop a normal system of nerves, leading to an accumulation of faeces in the colon following birth.

  ‘The most common associated conditions include Hirschsprung's disease and imperforate anus.’

  More example sentences

  • ‘Children with an organic cause for constipation, such as Hirschsprung's disease, were excluded.’
  • ‘Anorectal manometry is indicated to demonstrate the rectoanal inhibitory reflex and to rule out Hirschsprung's disease.’
  • ‘Rarely, vomiting is caused by disordered motility states, the most common of which is Hirschsprung's disease.’
  • ‘In children younger than one year of age, the possibility of Hirschsprung's disease must be considered.’