Meaning of Hurler's syndrome in English:

Hurler's syndrome

Pronunciation /ˈhəːləz/

noun

mass nounMedicine
  • An inherited condition arising from absence of an enzyme involved in mucopolysaccharide metabolism, resulting in severely impaired formation of bone and cartilage and malfunction of the brain and other organs.

    ‘Moreover, cord blood stem cells appear to repair more of the damage caused by Hurler's syndrome than does adult bone marrow.’
    • ‘The normal development of myelin sheaths is impaired in children born with certain inherited diseases, such as Tay-Sachs disease, Niemann-Pick disease, Gaucher's disease, and Hurler's syndrome.’
    • ‘If the disease is not stopped, children with Hurler's syndrome usually die by 5 to 10 years of age.’

Origin

1930s named after Gertrud Hurler (1889–1965), the Austrian paediatrician who first described it.