An inherited condition characterized particularly by skeletal changes (elongation of the limbs and digits and looseness of joints), displacement of the lens of the eye, and a tendency to develop aneurysms, especially of the aorta.‘Orthodontists also play a role in diagnosing systemic conditions that affect facial growth or development of the dentition, such as acromegaly or Marfan's syndrome.’
- ‘Causes of dissection include hypertension, Marfan's syndrome, trauma, Ehler's Danlos, coarctation, bicuspid aortic valve and relapsing polychondritis.’
- ‘None had had a previous aortic dissection or had a family history or clinical characteristics of Marfan's syndrome, and in no case was the aortic dissection secondary to chest trauma.’
- ‘Most interest has been focused on fibrillin, since it is present in the largest amounts and since mutations in the fibrillin gene are responsible for Marfan's syndrome.’
- ‘Younger patients with Marfan's syndrome may benefit from surgery in the subacute phase and avoid rupture of a residual saccular aneurysm in the future.’
1930s named after Antonin B. J. Marfan (1858–1942), French paediatrician.