Meaning of megaloblast in English:


Pronunciation /ˈmɛɡələ(ʊ)blɑːst/


  • A large, abnormally developed red blood cell typical of certain forms of anaemia, associated with a deficiency of folic acid or of vitamin B₁₂.

    ‘Enlarged red cells, called megaloblasts, are caused by vitamin B12 deficiency and folate deficiency.’
    • ‘Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.’
    • ‘Enlarged red cells derived from megaloblasts are a consequence of a deficiency of vitamin B12 or folic acid.’
    • ‘Finding megaloblasts in the blood can help to diagnose anaemia but does not determine the cause.’
    • ‘Megaloblastic anemia is characterized by the presence of megaloblasts in the bone marrow.’