noun

• A synthetic compound that interferes with cell growth and is used to treat leukaemia and other forms of cancer.

  Chemical formula: C₂₀H₂₂N₈O₅

  ‘Cancer drugs used for primary bone cancer include methotrexate, doxorubicin, and cisplatin.’

  More example sentences

  • ‘Treatment may include systemic steroids, intralesional steroid injection, antimalarials, or methotrexate.’
  • ‘Antimalarial drugs or immune response modifiers like methotrexate can reduce steroid dose and side effects.’
  • ‘Another combination is methotrexate plus cyclo-sporine and methotrexate.’
  • ‘The patient was treated with methotrexate and leukovorin calcium, and tumor lysis syndrome with acute renal failure occurred.’