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A lysergic acid derivative that acts as a selective serotonin receptor antagonist, and is sometimes used, usually in the form of its maleate, for the prevention of severe migraine and cluster headaches; 1-methyl- d- lysergic acid butanolamide, C₂₁ H₂₈ N₃ O₂.
1960s; earliest use found in American Journal of the Medical Sciences. From meth- + -yserg- + -ide.