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Meaning of metyrapone in English:

metyrapone

noun

Pharmacology

  • A compound that inhibits the enzyme 17β-hydroxylase and prevents synthesis of glucocorticoids and mineralocorticoids by the adrenal gland, used chiefly for assessment of feedback control of the hypothalamic-pituitary axis in adrenal disease, and sometimes in the treatment of Cushing's syndrome and resistant oedema; 2-methyl-1,2-di-3-pyridyl-1-propanone, C₅ H₄ N·CO·C(CH₃)₂ ·C₅ H₄ N.

Pronunciation

metyrapone

/mɪˈtɪrəpəʊn/ /mɪˈtʌɪrəpəʊn/

Origin

1960s; earliest use found in The Lancet. Probably from met- + -yr- + -a- connective + -p- + -one.