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Originally: impairment of the intellectual faculties; mental dullness or retardation. Later: inappropriate jocularity, as a sign of mental illness or neurological disease.
Late 17th century; earliest use found in Blankaart's Physical Dictionary. From post-classical Latin moria folly, foolishness (Erasmus) from ancient Greek μωρία from μωρός, μῶρος foolish + -ία.