noun

• 1Medicine
  Swelling of the skin and underlying tissues giving a waxy consistency, typical of patients with underactive thyroid glands.

  ‘Patients with myxedema present with rough skin of the palms, soles, elbows and knees, and yellow-orange discoloration of the skin, along with other signs of hypothyroidism.’

  More example sentences

  • ‘The differential diagnosis includes venous stasis dermatitis, pretibial myxedema, filariasis, and ichthyosis.’
  • ‘He supports this with reference to a retrospective analysis of the records of 50 patients with myxoedema.’
  • ‘The presence of goiter, coarse hair, dry skin, carotenemia, and myxedema indicates hypothyroidism.’
  • ‘I changed my hairdresser but the possibility of myxoedema did not enter my head.’

  1. 1.1The more general condition associated with hypothyroidism, including weight gain, mental dullness, and sensitivity to cold.