Meaning of pellagra in English:

pellagra

Pronunciation /pɛˈlaɡrə/ /pɛˈleɪɡrə/

noun

mass noun
  • A deficiency disease caused by a lack of nicotinic acid or its precursor tryptophan in the diet. It is characterized by dermatitis, diarrhoea, and mental disturbance, and is often linked to over-dependence on maize as a staple food.

    • ‘Those highly dependent on corn as a food might develop pellagra and this chronic disease, causing dermatitis, diarrhea, and ultimately dementia, battered the population of European corn growing regions during the nineteenth century.’
    • ‘Deficiency leads to pellagra, a condition characterized by dermatitis, diarrhea and certain mental health problems.’
    • ‘The troops suffered from malaria, dengue fever, beriberi, hookworm and pellagra.’
    • ‘We now know that a niacin or tryptophan deficiency causes pellagra.’
    • ‘Severe deficiency of vitamin B - 6 may lead to pellagra, a neurological illness with features of dementia.’
    • ‘Hypoproteinemia and pellagra are caused when tryptophan (ie, an essential amino acid) is used for serotonin production instead of for protein and niacin synthesis.’
    • ‘When was the last time that you met an American-born person suffering from rickets, scurvy, beriberi, pellagra, or any other disease caused entirely by malnutrition.’
    • ‘Nongovernment organizations have initiated public health programs such as the Rockefeller Foundation which undertook eradication of pellagra and hookworm.’
    • ‘A 67 year old Zambian woman presented to our mission hospital with diarrhoea, dementia, and dermatitis, which are the classic features of pellagra.’
    • ‘Despite differing reports about the initial symptoms of this wasting disease, pellagra is characterized by diverse clinical manifestations mainly involving the dermatological, gastrointestinal, and neurological systems.’
    • ‘In 1902, the American South was swept with an epidemic of pellagra (a niacin and tryptophan deficiency).’
    • ‘A deficiency of niacin causes the disease pellagra.’
    • ‘His work on pellagra saved thousands of lives.’
    • ‘He is best known for his work on the disease pellagra, the ‘scourge of the south,’ in which he discovered that the cause of pellagra was a dietary insufficiency, later identified as vitamin B niacin.’
    • ‘The occurrence of pellagra started to be associated from the mid 1700s with a poor diet of maize-meal without meat or milk in different parts of the world, and this link was still occurring in the US well into the twentieth century.’
    • ‘Inadequate amounts of this vitamin cause a disease called pellagra, which is characterized by skin disorders, weak muscles, diarrhea, and loss of appetite.’
    • ‘There, in the camp, he almost died of hunger, developed dystrophy and pellagra, and almost lost his central vision.’
    • ‘The severe symptoms, depression, dermatitis and diarrhea, are associated with the condition known as pellagra.’
    • ‘But due to peasant resistance and initiative, maize became the primary crop, supporting grain and livestock production and providing the peasant's major food, a dependence that later produced the scourge of pellagra.’
    • ‘The cutaneous changes were among the first symptoms of pellagra to appear in anorexia nervosa patients.’

Origin

Early 19th century from Italian, from pelle ‘skin’, on the pattern of podagra.

Pronunciation

pellagra

/pɛˈlaɡrə/ /pɛˈleɪɡrə/