1North American rare Any of several ericaceous shrubs formerly placed in the genus Andromeda, especially Leucothoe racemosa and Lyonia ligustrina; more fully "white pepperbush".
2North American Any of several fragrant-flowered shrubs of the genus Clethra (family Clethraceae) of eastern North America; especially C. alnifolia, sometimes grown as an ornamental; more fully "sweet pepperbush".
3Australian = mountain pepper .
Late 17th century (in an earlier sense). From pepper + bush.