A synthetic antihistamine drug derived from phenothiazine, used chiefly to treat the symptoms of allergies and motion sickness.
‘Causative medications are droperidol, diphenhydramine, meperidine, promethazine, atropine, and scopolamine.’
‘He was treated with promethazine and amoxicillin, and discharged.’
‘Lytic cocktail is a term used loosely to describe a fixed combination of meperidine, promethazine, and chlorpromazine intended typically for intramuscular use.’
‘Several antiemetics, such as metoclopramide, chlorpromazine, prochlorperazine, and promethazine, are regarded as safe for use during pregnancy.’
‘Metoclopramide, droperidol, prochlorperazine, and promethazine are commonly chosen rescue antiemetics.’
Origin
1940s from pro(pyl) + (di)meth(ylamine), a colourless gas + (phenothi)azine.
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