Meaning of tricyclic in English:


Pronunciation /trʌɪˈsʌɪklɪk/


  • (of a compound) having three rings of atoms in its molecule.

    ‘Quinacrine is a planar tricyclic compound with structural similarities to DMMB, yet it does not absorb red light.’
    • ‘In addition, all methyl sulfone containing compounds in the tricyclic class are very poorly bioavailable.’
    • ‘Clomipramine was equal to desipramine and both tricyclic agents were superior to placebo for amelioration of hyperactivity.’
    • ‘In addition to monocyclic shoots, there are also bicyclic ones, and on the branches in the canopy top there are even tricyclic vegetative shoots.’
    • ‘The danger of precipitating mania is reported to be greatest with tricyclic agents.’


usually tricyclics
  • Any of a class of antidepressant drugs having molecules with three fused rings.

    ‘However inspection of comparative studies in fall risk between SSRIs and tricyclics suggest these two antidepressant classes exhibit similar risks of fall.’
    • ‘Over half of the prescriptions were for the class antidepressants known as tricyclics, while four out of 10 were for SSRIs.’
    • ‘The most commonly prescribed antidepressant medications include the tricyclics and selective serotonin reuptake inhibitors.’
    • ‘Their effect on blood pressure can be worsened by taking them along with certain antidepressants, such as tricyclics.’
    • ‘There are several new antidepressants which work in a different way from SSRIs and tricyclics.’


Late 19th century from tri-‘three’ + Greek kuklos‘circle’ + -ic.