Meaning of trimethoprim in English:


Pronunciation /trʌɪˈmɛθə(ʊ)prɪm/


mass nounMedicine
  • A synthetic antibiotic used to treat malaria and respiratory and urinary infections (usually in conjunction with a sulphonamide).

    ‘Medicines used are sulfonamide with or without trimethoprim, furadantin, ampicillin, or the fluoroquinolones.’
    • ‘For urinary tract infection, we examined resistance to ampicillin or amoxicillin and trimethoprim.’
    • ‘At the same time we would also audit the prescribing of trimethoprim for urinary tract infections and the investigations and second visits associated with its use.’
    • ‘The most commonly applied antibiotics were doxycycline, erythromycin, and trimethoprim in combination with sulfamethoxazole, which are all considered broad-spectrum antibiotics.’
    • ‘Certain medicines, such as some antiepileptic drugs and the antibiotic drug trimethoprim, can interfere with folate levels.’


1960s from trimeth(yl) + o(xy-) + p(y)rim(idine).