anxious, disturbed, perturbed, troubled, bothered, distressed, concerned, upset, distraught, worried sick, disquieted, uneasy, ill at ease, fretful, fretting, agitated, in a state of agitation, nervous, edgy, on edge, like a cat on a hot tin roof, tense, overwrought, worked up, keyed up, strung out, jumpy, with one's stomach in knots, stressed, under stress