Meaning of valine in English:


Pronunciation /ˈveɪliːn/


mass nounBiochemistry
  • An amino acid which is a constituent of most proteins. It is an essential nutrient in the diet of vertebrates.

    Chemical formula: (CH₃)₂CHCH(NH₂)COOH

    ‘In sickle cell disease, the amino acid valine is substituted for glutamic acid in the beta-hemoglobin chain of hemoglobin.’
    • ‘When synthetic lysine is used in the lactation diet, care should be taken to ensure that methionine, valine, and threonine are not limiting.’
    • ‘Sickle cell anemia is caused by the replacement of glutamate by valine at the sixth position of the [beta] globin chain.’
    • ‘In contrast to valine, the long flexible side chains of leucine or methionine would make better probes of helix-helix interfaces due to the significant differences between free and restricted line shapes.’
    • ‘Glycine and valine exhibited isotopic values outside the range of our sampled end members.’


Early 20th century from val(eric acid)+ -ine.