Definition of channelopathy in English:

channelopathy

Pronunciation /tʃanəˈlɒpəθi/

noun

Medicine
  • Any of a diverse class of diseases or disorders caused by the dysfunction or impaired regulation of a particular type of membrane ion channel, especially in nerve or muscle cells.

    Such disorders and diseases have a range of causes including genetic mutation (e.g. in cystic fibrosis) and autoimmune conditions (e.g. in myasthenia gravis).

Origin

1990s; earliest use found in Neuromuscular Disorders. From channel + -o- + -pathy.