Definition of cimetidine in English:



  • An antihistamine drug which is used to treat stomach acidity and peptic ulcers. It is a sulfur-containing derivative of imidazole.

    ‘Acetaminophen, aspirin, cimetidine, ibuprofen and diphenhydramine are just a few drugs that might be affected by alcohol.’
    • ‘Examples of commonly used medications that may contain large amounts of sorbitol include acetaminophen, amantadine, cimetidine, and theophylline.’
    • ‘Most cases of indigestion can be treated successfully with medicines that reduce the excess acid, such as antacids and H - 2 antagonist drugs like cimetidine.’
    • ‘New peptic ulcers are treated with H2 blockers such as cimetidine or sucralfate.’
    • ‘A few small studies have supported medical management of such ulcers, but study participants were treated only with antacids and cimetidine.’
    • ‘Large doses of cimetidine must be medically supervised.’
    • ‘In severe cases, 300 mg of cimetidine may be added.’
    • ‘Suggested intravenous antihistamine pretreatment is diphenhydramine, in a dosage of 1 mg per kg, and cimetidine, in a dosage of 6 mg per kg.’
    • ‘Both cimetidine and ranitidine are effective in raising gastric pH above 4 to 5 and may prove useful in protecting against stress ulceration.’
    • ‘The absorption of cimetidine and ranitidine is accelerated when coadministered with cisapride.’
    • ‘This adverse reaction precludes the use of cimetidine in this patient.’
    • ‘Some experts advocate the addition of 25 mg of ephedrine and 300 mg of cimetidine orally one hour before the procedure.’
    • ‘Use of prophylactic cimetidine or tonsillectomy also may improve symptoms in some children.’
    • ‘Treatment with cimetidine was begun.’
    • ‘During the past year, the hospital identified cimetidine as its primary agent.’
    • ‘I have just recently read that cimetidine can cause impotence as a side effect.’
    • ‘Hyperbaric oxygen and cimetidine have been used in certain cases with good results.’
    • ‘In a large study of 874 patients with chronic duodenal ulcers, patients received either DGL, cimetidine, or antacids.’



/sīˈmedəˌdēn/ /saɪˈmɛdəˌdin/


1970s from ci- (alteration of cy- in cyano-) + met(hyl)+ -ide+ -ine.