Definition of clozapine in English:


Pronunciation /ˈklōzəˌpēn/ /ˈkloʊzəˌpin/


  • A sedative drug used to treat schizophrenia.

    ‘Our analysis suggests that antipsychotic drugs other than clozapine may be associated with myocarditis and cardiomyopathy.’
    • ‘Examples of surveillance programmes being written into drug licensing decisions include clozapine and alosetron.’
    • ‘The use of atypical drugs such as clozapine and olanzapine, which do not have this effect, may increase fertility rates.’
    • ‘At present, clozapine is the only antipsychotic drug licensed in the United Kingdom for treating patients who have responded poorly to standard antipsychotic treatment.’
    • ‘One drug, clozapine, is associated with reducing suicidal behaviour.’


From c(h)lo(ro)- + elements of benzodiazepine.