Definition of coloboma in English:


Pronunciation /ˌkäləˈbōmə/ /ˌkɑləˈboʊmə/


  • A congenital malformation of the eye causing defects in the lens, iris, or retina.

    ‘Newborns with aniridia or coloboma should have a formal eye examination.’
    • ‘Depending on the extent and location of the coloboma, there may be decreased visual acuity, nystagmus, strabismus, photophobia, and a loss of visual fields.’
    • ‘Complete coloboma is when all of the structures of the eye are involved; these are the choroid, the retina, the optic disk, the ciliary body, the macular and the iris.’


Mid 19th century modern Latin, from Greek kolobōma ‘part removed in mutilation’, from kolobos ‘cut short’.