Definition of creatine in English:


Pronunciation /ˈkrēətēn/ /ˈkriətin/ /ˈkrēət(ə)n/ /ˈkriət(ə)n/


  • A compound formed in protein metabolism and present in much living tissue. It is involved in the supply of energy for muscular contraction.

    A guanidine derivative, usually present as a phosphate; chemical formula: C₄H₉N₃O₂

    ‘It is going to lead to increases in the appearance, of proteins, such as creatine kinase in the bloodstream.’
    • ‘It improves the uptake of protein and other nutrients, such as creatine and glutamine.’
    • ‘Insulin helps to drive glucose, amino acids and creatine into muscle cells.’
    • ‘Protein manufacturers soon caught on and began adding creatine to protein shakes.’
    • ‘This ensures that creatine and insulin are present in the bloodstream at the same time.’


Mid 19th century formed irregularly from Greek kreas ‘meat’+ -ine.