Definition of cri du chat syndrome in English:

cri du chat syndrome

Pronunciation /ˌkriː də ˈʃɑː ˌsɪndrəʊm/


  • A rare congenital disorder resulting from deletion of part of the short arm of chromosome 5, characterized by microcephaly, facial abnormalities, severe mental retardation, and (in infants) a distinctive high-pitched mewing cry.


1960s; earliest use found in Cytogenetics. From French cri du chat + syndrome.