Definition of CRISPR in English:

CRISPR

Pronunciation /ˈkrispər/ /ˈkrɪspər/

noun

  • 1Biochemistry
    A segment of DNA containing short repetitions of base sequences, involved in the defense mechanisms of prokaryotic organisms to viruses.

    CRISPR sequences encode RNAs that can recognize specific target sequences in a genome, at which base pairs can be cut or added. They act in a complex with a specific protein that functions like a pair of molecular scissors, with which they are used as a tool in genetic engineering

    1. 1.1A genetic engineering tool that uses a CRISPR sequence of DNA and its associated protein to edit the base pairs of a gene.
      • ‘using the genome editing tool known as CRISPR, researchers were able to selectively silence two genes in human papillomavirus’

Origin

Early 21st century short for clustered regularly interspaced short palindromic repeat.