Definition of de novo in English:

de novo

adverb & adjective

  • Starting from the beginning; anew.

    as adverb ‘in a pure meritocracy, everyone must begin de novo’
    as adjective ‘a general strategy for de novo protein design’
    • ‘Both the Federal Reserve and the Office of the Comptroller of the Currency recommend that Congress remove outdated barriers to de novo interstate branching.’


Latin, literally ‘from new’.


de novo

/deɪ ˈnəʊvəʊ/ /diː ˈnəʊvəʊ/