Definition of decarboxylate in English:


transitive verb

[with object]
  • 1Chemistry
    Eliminate a carboxylic acid group from (an organic compound)

    ‘heating at 100°C in dryness decarboxylates the proteins to yield glutamic acid’
    • ‘Coproporphyrinogen III is transported to the interior of the mitochondrion, where 2 propionate residues are decarboxylated, yielding vinyl substituents on the 2 pyrrole rings.’
    • ‘Thus, malate produced following PEP carboxylation is readily decarboxylated and the CO 2 released.’
    • ‘In this compartment, called the matrix, the pyruvic acid is decarboxylated to a two-carbon acetyl group, releasing a CO 2 molecule, and is enzymatically joined to Coenzyme A, a large carrier molecule.’
    • ‘Malate formed by PEPC can either be used in the citric acid cycle or it can be decarboxylated to provide pyruvate and subsequently acetyl-CoA.’
    • ‘Pyruvate is first decarboxylated to produce acetaldehyde and carbon dioxide, catalyzed by pyruvate decarboxylase.’
    1. 1.1no object Undergo the process of decarboxylation.
      ‘unstable carbamic acid decarboxylates to yield the amine’
      • ‘After electron transfer the product decarboxylates resulting in a ketylbiradical III that has a life time of about 4 s, long enough to reduce oxygen to superoxide.’



/ˌdēkärˈbäksəlāt/ /ˌdikɑrˈbɑksəleɪt/