Definition of derange in English:



[with object]
  • 1Make (someone) insane.

    ‘that business last month must have deranged him a bit’
    • ‘Privately, she wondered if they were watching her to see if she would have a breakdown or if she was mentally deranged or something, but she said nothing to that effect.’
    • ‘Meanwhile, police based on preliminary investigation ruled out the possibility of him being mentally deranged.’
    • ‘His unhinged language suggested that persecution mania briefly deranged him.’
    • ‘The boy was from a good family but he was deranged in some way: he wouldn't eat, he quarrelled with everyone, and he refused to go out to work.’
    • ‘However, there is a distinct possibility that I am slightly deranged, so it could just be me that looks at life that way.’
    • ‘During this period many of the friends of the individual affected supposed him to be only very eccentric; while some, who had opportunities of observing him closely, were convinced that he was deranged.’
    • ‘Imagine going home to your family and friends and being told you were deranged!’
    • ‘No wonder I am deranged and will probably have to spend a big portion of my adult earnings in therapy.’
    • ‘And if you're deranged enough to forgo the spa treatments and the excuse to not wear real clothes for two days, there's golf, horse riding and mountain-biking on offer nearby.’
    • ‘Well I'm glad that's the only reason you're staring at me like I'm mentally deranged.’
    • ‘You are seriously deranged if you think I'm going to walk thirty miles!’
    • ‘Jordan looked at his wife, as if she was deranged.’
    • ‘I was so deranged that I actually considered getting therapy for myself.’
    • ‘Some of the people in the computer room were glancing at me like I was deranged.’
    • ‘Also, it could be why he is deranged now, since he obviously isn't on the medication.’
    • ‘Maybe it's just some psychotic or bored and deranged person making a prank call.’
    • ‘The father got custody of her because the mother is mentally deranged and the police think that this girl is in grave harm.’
    • ‘The psychologist concluded that the soldier was deranged, and wrote out his discharge from the army.’
    • ‘And I never dared to ask my parents or teacher for fear of being termed mentally deranged.’
    • ‘There was something demented and deranged about him, a little dark, a little disturbing, that actually scared her.’
    insane, mad, of unsound mind, out of one's mind, not in one's right mind, disturbed, unbalanced, unhinged, unstable, crazed, demented, irrational, berserk, frenzied, maniac, lunatic, psychopathic, certifiable, raving, raving mad
    1. 1.1Cause (something) to act irregularly.
      ‘stress deranges the immune system’
      • ‘In scoliosis, the anatomy is deranged not only at each vertebral level but also between the convex and concave sides of the curve in the spine.’
      • ‘As when an individual soldier lost his balance, many flailing and falling soldiers deranged the enemy formation causing a serious decrease in the enemy's own firepower.’
      • ‘Autosomal genes often showed deranged regulatory levels, indicating they were in pathways perturbed by X chromosomal changes.’
      • ‘My memory was deranged because of the new program.’
      • ‘The group kicked proceedings off, squeezing their way into hormonally deranged teen hearts, with a crisp and punchy pop-punk-pounce.’
      • ‘In other patients, the genes preparing neurofilament proteins that support the nerve fibers are deranged.’
      • ‘Sometimes the stress deranges the managers' senses.’
      • ‘It is well known that stress deranges the immune systems of human beings and non-human primates alike.’
      • ‘In addition, antibiotic treatment deranges protective flora and antibiotic resistant microbial strains emerge.’
      • ‘Several drugs have been shown to derange macrophage functions, bactericidal efficacy and production and secretion of cytokines.’
      • ‘Unforeseen accidents may derange our most profound schemes of policy.’
  • 2archaic Intrude on; disturb.

    ‘I am sorry to have deranged you for so small a matter’
    • ‘From her gauze veiling the young woman spoke:-- "We are sorry to derange you. The guard made a mistake. Pardon!"’
    throw into confusion, throw into disorder, throw into disarray, cause confusion in, cause turmoil in, play havoc with, derange, turn upside-down, make a mess of


Late 18th century from French déranger, from Old French desrengier, literally ‘move from orderly rows’.