Definition of enterohepatic in English:



  • Relating to or denoting the circulation of bile salts and other secretions from the liver to the intestine, where they are reabsorbed into the blood and returned to the liver.

    • ‘Bile salts are retrieved from the gut by the terminal ileum, and this enterohepatic circulation is essential for maintenance of the bile salt pool.’
    • ‘A portion of conjugated and unconjugated steroids also passes into bile, some of which may be reabsorbed via enterohepatic circulation.’
    • ‘One proposed mechanism is interruption of the enterohepatic circulation of estrogen as a result of reduced bacterial hydrolysis in the gastrointestinal tract.’
    • ‘The rest either undergoes enterohepatic recycling or demethylation by microflora in the intestine and immune system and eventual elimination through the feces.’
    • ‘Patients with delayed gastrointestinal transit time may be more susceptible to these side effects, due to enterohepatic cycling and reabsorption of licorice metabolites.’