Definition of epitope in English:

epitope

noun

Biochemistry
  • The part of an antigen molecule to which an antibody attaches itself.

    • ‘On cell-surface glycoproteins, the epitope structure of TF antigen is linked to either serines or threonines.’
    • ‘The loci of the known epitopes of the antibodies used are shown diagrammatically in Fig.1.’
    • ‘In all the experiments on native titin, the molecule was attached to two beads, each labeled with an antibody to a different epitope.’
    • ‘We chose to consider residue charge because of evidence that the pattern of residue charges is important in determining epitopes for antibodies.’
    • ‘Even in the case of microbial antigens not found in vertebrates such as lipopolysaccharides, it should be noted that peptide epitopes can mimic bacterial carbohydrates and DNA.’

Origin

1960s from epi-‘upon’ + Greek topos ‘place’.

Pronunciation

epitope

/ˈɛpɪtəʊp/