Definition of histiocyte in English:


Pronunciation /ˈhistēəˌsīt/ /ˈhɪstiəˌsaɪt/


  • A stationary phagocytic cell present in connective tissue.

    ‘Occasional plasma cells, histiocytes, and eosinophils were also present.’
    • ‘Multinucleated giant cells and single epithelioid histiocytes were often present in association with granulomas.’
    • ‘Among nonneoplastic cells, only hepatocytes and rare plasma cells and histiocytes show cytoplasmic positivity.’
    • ‘Small aggregates of lymphocytes, plasma cells, and histiocytes were dispersed within the tumor.’
    • ‘Small clusters of lymphocytes and histiocytes were present throughout the tumor.’


Early 20th century from Greek histion (diminutive of histos ‘tissue, web’) + -cyte.