Definition of homolog in English:


(also homologue)

Pronunciation /ˈhōməˌlôɡ/ /ˈhoʊməˌlɔɡ/ /ˈhäməˌlôɡ/ /ˈhɑməˌlɔɡ/


  • A homologous thing.

    ‘During meiosis I, the replicated sister chromatids pair with their homologs but segregate as a single unit.’
    • ‘The distribution of homologues among different taxa is seen as a consequence of their phylogenetic relationship.’
    • ‘It ensures proper chromosome segregation by forming a physical link between homologs during meiosis.’
    • ‘Several studies show involvement of telomeres in the pairing of homologs during meiosis.’
    • ‘The most important point is that this gene has no homologues in other organisms, making it an attractive drug target.’
    • ‘We attempted to glean information about their functions by searching for possible homologs in other organisms.’
    counterpart, analogue, equivalent, likeness, correspondent, match, twin, duplicate, equal, coequal, mirror


Mid 19th century from French, from Greek homologos (see homologous).