Definition of imidazole in English:



  • A colorless crystalline compound with mildly basic properties, present as a substituent in the amino acid histidine.

    a heterocyclic compound; chemical formula: C₃H₄N₂

    ‘The quenching effect is attributed to the presence of proximal imidazole and pyrrole groups in their three-dimensional structures.’
    • ‘Conventional modeling of the amino acid side chains was used, that is, the zinc ligands aspartate, cysteinate, and histidine were modeled by acetate, methylthiolate, and imidazole, respectively.’
    • ‘In contrast, the lipid portion of the cuticular membrane, the cuticle proper and the matrix of the cuticular layer react with imidazole.’
    • ‘The trend in the photophysical properties found in the emission spectra parallels the changes in the photochemical properties with the electron-donating or electron-withdrawing power of the substituent on the imidazole ligand.’
    • ‘The thermal motion of imidazole axial ligands has also been investigated by electron paramagnetic and nuclear magnetic resonance spectra in proteins and synthetic models in homogeneous solution.’



/ˌiməˈdazōl/ /ˌɪməˈdæzoʊl/


Late 19th century from imide+ azo-+ -ole.