1The state of feeling annoyed, impatient, or slightly angry.
annoyance, infuriation, exasperation, vexation, indignation, impatience, crossness, displeasure, resentment, gall, chagrin, piqueView synonyms
- ‘much to my irritation, Chris fell asleep’
- 1.1A thing that annoys or irritates someone.
irritant, source of irritation, source of vexation, annoyance, source of annoyance, thorn in someone's flesh, thorn in someone's side, pinprick, pest, bother, trial, torment, plague, inconvenience, nuisance, bugbear, menaceView synonyms
- ‘the minor irritations of life’
2Inflammation or other discomfort in a body part caused by reaction to an irritant substance.
- ‘some chemicals cause a direct irritation to the skin leading to dermatitis’
- 2.1Biology The stimulation of an organism, cell, or organ to produce an active response.
Late Middle English from Latin irritatio(n-), from the verb irritare (see irritate).
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