Definition of leptin in English:



mass nounBiochemistry
  • A protein produced by fat cells that is a hormone acting mainly in the regulation of appetite and fat storage.

    • ‘Obese people are also believed to have a faulty receptor in their brains, which is meant to measure levels of leptin, a protein produced by fatty tissue.’
    • ‘Our bodies are thought to have a built-in system to measure levels of a key protein, leptin, which is produced in fatty tissue.’
    • ‘Apart from its role in regulation of fat metabolism, leptin may also regulate insulin release as part of an adipoinsular feedback.’
    • ‘Sleep deprivation lowers leptin, a blood protein that suppresses appetite and seems to affect how the brain senses when the body has had enough food.’
    • ‘Fat cells produce leptin, a protein known to help trigger puberty.’


1990s from Greek leptos ‘fine, thin’ + -in.