Definition of Lesch-Nyhan in English:

Lesch-Nyhan

Pronunciation /lɛʃˈnʌɪhən/

See synonyms for Lesch-Nyhan

noun

Medicine
  • Attributive Especially in "Lesch-Nyhan syndrome". Designating an inherited disorder of purine metabolism characterized by abnormally high levels of uric acid, compulsive biting of the lips and fingers, mental disability, and involuntary muscular movements.

Origin

1960s. From the names of Michael Lesch and William Leo Nyhan (b. 1926), U.S. physicians, who described the syndrome in 1964 (in Amer. Jrnl. Med 36 561).