Definition of main line in English:

main line

(also mainline)

Pronunciation /ˌmān ˈlīn/ /ˌmeɪn ˈlaɪn/

Translate main line into Spanish


  • 1A chief railroad line.

    ‘the crash blocked traffic on the main line’
    • ‘a main-line station’
    1. 1.1North American A chief road or street.
      main route, trunk route, main road, trunk road, main line, trunk line, high road, highway
  • 2informal A principal vein as a site for a drug injection.

transitive verb

[with object]informal
  • Inject (a drug) intravenously.

    • ‘Mariella mainlines cocaine five times a day’
    • ‘he started mainlining on heroin’
    • ‘Her performance electrifies the story of the model who died of the virus she probably picked up by mainlining heroin.’
    • ‘It begins with the great detective, Sherlock Holmes, mainlining on a 7% solution of cocaine.’
    • ‘She had mainlined morphine, but never more than 10 cc.’
    • ‘Today, d-Meth is the most popular type in the U.S. and is the most potent, has far less side effects and does not need to be mainlined.’
    • ‘Percodan is similar to codeine but is usually mainlined.’
    administer, introduce