Alternative name: 2-methyl-1,4-naphthoquinone; chemical formula: C₁₁H₈O₂
‘This medium is prepared twice each week and is complemented with 8% sheep blood, menadione, and gentamicin, making this medium selective for anaerobes.’
‘The K vitamins exist naturally as K 1 in green vegetables and K 2 produced by intestinal bacteria and K 3 is synthetic menadione.’
‘After absorption, menadione is thought to become alkylated into biologically active isoprenylated menaquinones.’
‘Hepatoma-bearing rats receiving intraperitoneal injections of menadione (10 mg / 2mL weekly for four weeks) demonstrated an increased survival rate of 60 days compared to 17 days for controls (five of 16 lived longer than controls).’
‘Using concentrations that had no effect on cell growth, we found that menadione had no significant effect on recombination under the conditions tested in either the wild-type or BER mutant backgrounds.’
Origin
1940s from me(thyl) + na(phthalene) + the suffix -dione, used in names of compounds containing two carbonyl groups.
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