Definition of metaphase in English:



  • The second stage of cell division, between prophase and anaphase, during which the chromosomes become attached to the spindle fibers.

    ‘The events in this stage of the cell cycle leading to cell division are prophase, metaphase, anaphase and telophase.’
    • ‘The most direct way to assess chromosomal aneuploidy is to evaluate chromosome numbers in metaphase cells.’
    • ‘Chromosome loss takes place by lagging of chromosomes at metaphase, for example because spindle fibres may fail to attach to a chromosome.’
    • ‘These tests score either chromosomal structural aberrations at metaphase or micronuclei at interphase.’
    • ‘The problem is greatest at mitotic metaphase, when chromosomes are shortest and neighboring signals are thus closest.’



/ˈmedəˌfāz/ /ˈmɛdəˌfeɪz/