Definition of metaplasia in English:


Pronunciation /ˌmedəˈplāZH(ē)ə/ /ˌmɛdəˈpleɪʒ(i)ə/


  • Abnormal change in the nature of a tissue.

    ‘intestinal metaplasia’
    • ‘The remaining 9 cases showed the coexistence of antral-type metaplasia, intestinal metaplasia, and dysplasia in the same specimen.’
    • ‘The antral mucosa showed pancreatic acinar cell metaplasia and intestinal metaplasia.’
    • ‘The existence of gastric lymphoma and intestinal metaplasia was observed in the same or different tissue fragments in most endoscopic biopsies.’
    • ‘Antral-type and intestinal metaplasia may represent local responses to chronic injury secondary to the presence of gallstones and inflammation.’
    • ‘However, a small series of 93 patients with an initial diagnosis of intestinal metaplasia were followed prospectively with endoscopy and biopsy.’


Late 19th century modern Latin, from German Metaplase, based on Greek metaplassein ‘mold into a new form’.