Definition of methysergide in English:

methysergide

Pronunciation /mɛθɪˈsəːdʒʌɪd/

noun

Pharmacology
  • A lysergic acid derivative that acts as a selective serotonin receptor antagonist, and is sometimes used, usually in the form of its maleate, for the prevention of severe migraine and cluster headaches; 1-methyl- d- lysergic acid butanolamide, C ₂₁ H ₂₈ N ₃ O ₂.

Origin

1960s; earliest use found in American Journal of the Medical Sciences. From meth- (in methyl see note s.v. meth-) + -yserg- + -ide.