Definition of monoclonal in English:


Pronunciation /ˌmänəˈklōnl/ /ˌmɑnəˈkloʊnl/


  • Forming a clone that is derived asexually from a single individual or cell.

    ‘Whether polyclonal proliferations progress to monoclonal lymphomas has not been proven.’
    • ‘Evaluation of the bone marrow revealed a small monoclonal population of cytoplasmic kappa light chain-restricted plasma cells in an otherwise normocellular marrow.’
    • ‘Pollen analysis enables the honey producer to identify whether the honey is monoclonal or polyclonal.’
    • ‘Additionally, a polyclonal intracerebral inflammatory response may precede the proliferation of monoclonal malignant lymphoid cells.’
    • ‘Herein, we report a case of monoclonal B-cell proliferation involving lymph nodes, bone marrow, and peripheral blood in a patient with Whipple disease.’