Definition of nalidixic acid in English:
nalidixic acid
noun
MedicineA synthetic compound which inhibits the multiplication of bacteria, used chiefly to treat urinary infections.
A heterocyclic compound; chemical formula: C₁₂H₁₂N₂O₃
‘In India, almost 100% of the healthy population carry bacteria that are resistant to ampicillin, trimethoprim, nalidixic acid, and chloramphenicol.’- ‘The original quinolone antibiotics included nalidixic acid, cinoxacin and oxolinic acid (no longer available in the United States).’
- ‘There has also been a change in the antimicrobial susceptibility pattern; resistance to ampicillin and nalidixic acid has changed in recent times.’
- ‘The organism isolated was resistant to ampicillin, cotrimoxazole, nalidixic acid and norfloxacin.’
- ‘There was no association between nalidixic acid and chloramphenicol susceptibility.’
Pronunciation
Origin
1960s nalidixic by rearrangement of elements from naphthalene, carboxylic, and di- (forming the systematic name).
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