Definition of nalidixic acid in English:

nalidixic acid


  • A synthetic compound which inhibits the multiplication of bacteria, used chiefly to treat urinary infections.

    A heterocyclic compound; chemical formula: C₁₂H₁₂N₂O₃

    ‘In India, almost 100% of the healthy population carry bacteria that are resistant to ampicillin, trimethoprim, nalidixic acid, and chloramphenicol.’
    • ‘The original quinolone antibiotics included nalidixic acid, cinoxacin and oxolinic acid (no longer available in the United States).’
    • ‘There has also been a change in the antimicrobial susceptibility pattern; resistance to ampicillin and nalidixic acid has changed in recent times.’
    • ‘The organism isolated was resistant to ampicillin, cotrimoxazole, nalidixic acid and norfloxacin.’
    • ‘There was no association between nalidixic acid and chloramphenicol susceptibility.’


nalidixic acid

/ˌnāliˌdiksik ˈasəd/ /ˌneɪlɪˌdɪksɪk ˈæsəd/


1960s nalidixic by rearrangement of elements from naphthalene, carboxylic, and di- (forming the systematic name).