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A bitter alkaloid, C₃₇ H₄₀ N₂ O₆, originally isolated from the bark of the root of the barberry Berberis vulgaris.
Mid 19th century; earliest use found in Robert Thomson (1810–1864), medical officer of health. From German Oxyacanthin from post-classical Latin oxyacantha, name for Berberis vulgaris + German -in.