Definition of polymerase in English:


Pronunciation /pəˈlimərāz/ /pəˈlɪməreɪz/


  • An enzyme which brings about the formation of a particular polymer, especially DNA or RNA.

    See also transcriptase

    ‘DNA polymerase’
    • ‘Replicative DNA polymerases are very accurate enzymes with error rates usually in the range of 10-5 per replicated nucleotide.’
    • ‘In contrast to the phage polymerases, RNA polymerases from higher organisms have a much more complex subunit structure than the bacterial enzymes.’
    • ‘The presence of the histones and CpG methylation most affect accessibility of the chromatin to RNA polymerases and transcription factors.’
    • ‘Promoter sequences promote the ability of RNA polymerases to recognize the nucleotide at which initiation begins.’
    • ‘These complexes regulate the interaction of RNA polymerases and DNA elements within promoters.’